null

SMILES Cn1cnc2c(nc(cc12)-c1ccc(CCCO)c(c1)C(F)(F)F)C#N

InChI Key InChIKey=JDJQLDQXYPUJRN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323258   

TargetCathepsin S(Homo sapiens (Human))
Merck Sharp & Dohme B.V.

US Patent
LigandPNGBDBM50323258(6-(4-(3-hydroxypropyl)-3-(trifluoromethyl)phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:The inhibitory activity of the compounds of the invention was demonstrated in vitro by measuring the inhibition of recombinant human Cathepsin S as f...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3CTTUS Patent
TargetCathepsin S(Homo sapiens (Human))
Merck Sharp & Dohme B.V.

US Patent
LigandPNGBDBM50323258(6-(4-(3-hydroxypropyl)-3-(trifluoromethyl)phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323258(6-(4-(3-hydroxypropyl)-3-(trifluoromethyl)phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed