null

SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key InChIKey=UUROSJLZNDSXRF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50323654   

TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50323654(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DKPPubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50323654(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XTVPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£mia, Inc.

Curated by ChEMBL
LigandPNGBDBM50323654(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of phospho-p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40W66PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£mia, Inc.

Curated by ChEMBL
LigandPNGBDBM50323654(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40W66PubMed
TargetScavenger receptor class B member 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50323654(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3TJ2PubMed