null
SMILES CN1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(N)sc3c2)c2c(N)ncnc12
InChI Key InChIKey=UNSGOTITAWKECZ-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50323732
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:Inhibition of p110alphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of p110deltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair