null

SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(C)CC1

InChI Key InChIKey=VSKQPWCCYSFMOY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323809   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323809(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08H1PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323809(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of G9a assessed as hydrolysis of S-adenosyl-L-homocysteine after 2 mins by SAHH-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q237793PPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323809(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08H1PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323809(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q237793PPubMed