null

SMILES CCOC(=O)c1cn2c(c(CN)c(C)nc2n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=IXOXZCSVVMIYCV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50324514   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi:  11.7nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi: >30nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataKi: >30nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182PXPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21W96PubMed