null

SMILES FC(F)Oc1cccc(c1)-c1cc(COc2ccc(CCC#N)cc2)cc2cccnc12

InChI Key InChIKey=BUHIJXWAPNJKFJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325800   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TVZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TVZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TVZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TVZPubMed