null
SMILES CNC(=O)c1ncn-2c1COc1c(CCN3CCN(CC3)c3cccc4nc(C)ccc34)cccc-21
InChI Key InChIKey=APQBIBMHRHYQIJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50326132
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataKi: >7.94E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes measured immediatelyMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes measured after incubationMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes measured immediatelyMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes measured after incubationMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes measured after incubationMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant CYP2C19 preincubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using diethoxyflourescein as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant CYP1A2 preincubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant CYPD6 preincubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using diethoxyflourescein/7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human ERG tail current by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes measured immediatelyMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant CYP2C9 preincubated for 10 minsMore data for this Ligand-Target Pair