null
SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cccnc2[nH]1)C(F)(F)F
InChI Key InChIKey=WFIFLFARTXGDFP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50326937
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity to glucocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluore...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Transrepression activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to progesterone receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled RU-486 by fluorescence po...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Binding affinity to mineralocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by flu...More data for this Ligand-Target Pair