null

SMILES Fc1ccccc1C1=Nc2cn[nH]c2Nc2ccc(cc12)C#N

InChI Key InChIKey=HVAQMHFWXFSGJF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328256   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed