null

SMILES CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC(C)C)ccc12

InChI Key InChIKey=ASYDIUHFIWWNJR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329844   

TargetEndothelin-1 receptor(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50329844(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]ET1 from ETA receptor expressed in african green monkey CCL-81 cells monolayerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34XPPPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50329844(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)copy SMILEScopy InChI
Affinity DataIC50: 713nMAssay Description:Antagonist activity at ETB receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S21PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50329844(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Antagonist activity at ETA receptor (unknown origin) expressed in membranes by radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S21PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50329844(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34XPPPubMed