null

SMILES Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12

InChI Key InChIKey=DNKYHHFCPXKFIY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50330722   

TargetNADPH oxidase 1(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataKi:  165nMAssay Description:Inhibition of human NOX1 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataKi:  165nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of human NOX2 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of xanthine oxidase by invitro enzymatic assay in presence of xanthineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed