null

SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O

InChI Key InChIKey=GKEYKDOLBLYGRB-LGMDPLHJSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331023   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GWFPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GWFPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GWFPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GWFPubMed