null

SMILES CS(=O)(=O)c1c(CCc2ccccc2)c2cc(OCC(=O)NCc3ccc(Cl)c(Cl)c3)ccc2[nH]c1=O

InChI Key InChIKey=YLOXHWSGECHWMF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50331921   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331921(CHEMBL1290543 | N-(3,4-dichlorobenzyl)-2-(3-(methy...)copy SMILEScopy InChI
Affinity DataKi:  172nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q60PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331921(CHEMBL1290543 | N-(3,4-dichlorobenzyl)-2-(3-(methy...)copy SMILEScopy InChI
Affinity DataKi:  211nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q60PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331921(CHEMBL1290543 | N-(3,4-dichlorobenzyl)-2-(3-(methy...)copy SMILEScopy InChI
Affinity DataKi:  315nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q60PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331921(CHEMBL1290543 | N-(3,4-dichlorobenzyl)-2-(3-(methy...)copy SMILEScopy InChI
Affinity DataKi:  811nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q60PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331921(CHEMBL1290543 | N-(3,4-dichlorobenzyl)-2-(3-(methy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH58261 from human adenosine A2A receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q60PubMed