null
SMILES Nc1c2c(cn(C3CCC3)c2=O)[nH]c2c(cccc12)-c1ncccn1
InChI Key InChIKey=ZCQOZHJHIVMMEC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50332374
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H]flunitrazepam from human alpha2beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]flunitrazepam from human alpha5beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 34nMAssay Description:Binding affinity to human alpha2beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 77nMAssay Description:Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 206nMAssay Description:Binding affinity to human alpha5beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair