null

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(OC(=O)N(CCCl)CCCl)ccc34)[C@@H]1CC[C@@H]2OP(O)(O)=O

InChI Key InChIKey=ADFOJJHRTBFFOF-RBRWEJTLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50333645   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944ZMPubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of recombinant SHP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944ZMPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 6.24E+4nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944ZMPubMed
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as inhibition of Ins(1,3,4,5)P4 production using Ins(1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CZMPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataKd:  8.40E+3nMAssay Description:Binding affinity to recombinant SHP2 by surface plasmon responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944ZMPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92G9PPubMed
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CZMPubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944ZMPubMed