null

SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(Oc3ccccc3)cc2)C1=O

InChI Key InChIKey=TXGWLQVCPVHGKO-GDNBJRDFSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334181   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7MKCPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 6.39E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7MKCPubMed