null

SMILES CNC[C@H]1C[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1

InChI Key InChIKey=NDCNHLIWHOBKGK-WBMJQRKESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50334777   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sepracor Inc.

Curated by ChEMBL
LigandPNGBDBM50334777(CHEMBL1642908 | cis-1-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed