null

SMILES N[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12

InChI Key InChIKey=OBKCQTGBMZHBFE-CQSZACIVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50334918   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 138nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FWSPubMed