null
SMILES Nc1nc2c(Cl)cccc2s1
InChI Key InChIKey=OEQQFQXMCPMEIH-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50335099
Affinity DataKi: 7.90E+4nMAssay Description:Inhibition of Leishmania major PTR1 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
IOTA Pharmaceuticals
Curated by ChEMBL
IOTA Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.10E+5nMAssay Description:Inhibition of N-terminal 6xHis-tagged PDE10A (unknown origin) expressed in BL21 (DE3) RIL cells using 3',5'-cGMP as substrate by microcalorimetric as...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
IOTA Pharmaceuticals
Curated by ChEMBL
IOTA Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.10E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
IOTA Pharmaceuticals
Curated by ChEMBL
IOTA Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.10E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Leishmania major PTR1More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Leishmania major)
Rutgers University
Curated by ChEMBL
Rutgers University
Curated by ChEMBL
Affinity DataIC50: 1.39E+6nMAssay Description:Inhibition of Leishmania major DHFRMore data for this Ligand-Target Pair