null

SMILES OC(=O)c1cc2c(-c3cn(CCCC(=O)Nc4cccc5ccccc45)nn3)c(oc2cc1O)-c1ccccc1

InChI Key InChIKey=RSPKMGDZBNPGGF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50335895   

TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Competitive inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N017XWPubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataKi:  3.39E+4nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN38Z0PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of lymphoid-specific tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Lyp-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3DZQPubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of PTP-Meg2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of FAP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of VHRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of HePTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N017XWPubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N016T4PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of SHP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QJDPubMed