null

SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UWPLTDHTKJMSCU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335968   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataKi:  7.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2JJQPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of the University of California

US Patent
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 148nMAssay Description:Trans-diphenylpropene oxide is used in a radiometric competitive assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D7MUS Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20865KBPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20865KBPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of the University of California

US Patent
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 28.9nMAssay Description:fluoresence competitive assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D7MUS Patent