null

SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=KSAUCBGUWGWPDL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50340726   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0NJSPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production after 2 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2PMNPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2PMNPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Inhibition of 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7T9NPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Inhibition of 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7T9NPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.14nM IC50: 4.61nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7N4BUS Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7N4BUS Patent