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SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1

InChI Key InChIKey=RUPXKSLKGSSZCP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50343141   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M9WPubMed
TargetFree fatty acid receptor 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  19nMAssay Description:Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M045RNPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  18.6nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MRWPubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at GPR120 assessed as stimulation of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D1HPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  12.9nMAssay Description:Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z45P4PubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z45P4PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M9WPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)copy SMILEScopy InChI
Affinity DataEC50:  18.6nMAssay Description:Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D1HPubMed