null

SMILES Cn1c(CN2CCC(CC2)c2ccc(Cl)cc2F)nc2ccccc12

InChI Key InChIKey=ZOSDMAHANBIICB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343305   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343305(2-((4-(4-Chloro-2-fluorophenyl)piperidin-1-yl)meth...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343305(2-((4-(4-Chloro-2-fluorophenyl)piperidin-1-yl)meth...)copy SMILEScopy InChI
Affinity DataEC50:  7.60nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed