null

SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IORJDNYKXIMYCK-WMLDXEAASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343319   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343319(CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343319(CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343319(CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...)copy SMILEScopy InChI
Affinity DataEC50:  111nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343319(CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...)copy SMILEScopy InChI
Affinity DataEC50:  111nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed