null
SMILES C[C@H]1COCCN1c1nc(nc2c1COC2(C)C)-c1ccc(NC(=O)NC2COC2)cc1
InChI Key InChIKey=BAPFSLSWVWETLT-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50343768
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of mTOR in human NCI-PC3 cells assessed as inhibition of p70S6k phosphorylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of mTor in human NCI-PC3 cells assessed as inhibition of Akt phosphorylation at serine473 by electrochemiluminescence assayMore data for this Ligand-Target Pair