null

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2c(CO[C@]2(C)CCO)c(n1)N1CCOCC1

InChI Key InChIKey=MMRPGKGGMCYSNW-JOCHJYFZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343778   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50343778((R)-1-ethyl-3-(4-(7-(2-hydroxyethyl)-7-methyl-4-mo...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6XRHPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50343778((R)-1-ethyl-3-(4-(7-(2-hydroxyethyl)-7-methyl-4-mo...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of mTOR in human NCI-PC3 cells assessed as inhibition of p70S6k phosphorylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6XRHPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50343778((R)-1-ethyl-3-(4-(7-(2-hydroxyethyl)-7-methyl-4-mo...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of mTor in human NCI-PC3 cells assessed as inhibition of Akt phosphorylation at serine473 by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6XRHPubMed