null

SMILES COc1ccc(cc1)-n1cnc2c(sc3nccc(NCC#C)c23)c1=O

InChI Key InChIKey=WIAAIYJUCDAKFY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50345949   

TargetMetabotropic glutamate receptor 1(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345949(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081SJPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50345949(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56MDJPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345949(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081SJPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50345949(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081SJPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50345949(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56MDJPubMed