null
SMILES [O-][n+]1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
InChI Key InChIKey=QSSHEITWSXIQFH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50346237
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A assessed as incorporation of [gamma-33P]-ATP into histone H1 substrate after 30 mins by scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 assessed as incorporation of [gamma-33P]-ATP into histone H1 substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in insect cells assessed as incorporation of [gamma-33P]-ATP in to pRB fragment (773 to 928) ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain CK1 assessed as incorporation of [gamma-33P]-ATP into RRKHAAIGpSAYSITA substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli assessed as assessed as incorporation of [gamma-33P]-ATP into myelin bas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at NOP receptor in Swiss mouse vas deferens by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at human B2 receptor transfected in CHO cells assessed as ability to antagonize BK-induced inositol-phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human M3 receptor assessed as inhibition of carbachol bindingMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cellsMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against adrenergic Alpha-1D receptor in rat thoracic aorta assessed as noradrenaline-induced responseMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at M3 muscarinic receptor in guinea pig assessed as effect on carbachol-induced trachea contractionMore data for this Ligand-Target Pair
In DepthDetails
TargetGlycogen synthase kinase 3(Plasmodium falciparum (isolate 3D7))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum GSK3More data for this Ligand-Target Pair