null

SMILES COc1ccccc1-c1ccc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nn12

InChI Key InChIKey=LLSXHTXXTKDPRH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50353052   

TargetInsulin receptor(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant ALK assessed as phosphorylated product using PLC-gamma/GST substrate by modified ELISA methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human recombinant JAK2 using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5NM2PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human recombinant JAK2 using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5NM2PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cephalon, Inc.

Curated by ChEMBL
LigandPNGBDBM50353052(CHEMBL1822515)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed