null

SMILES NC(=O)c1cnc(N[C@H](C2CC2)C(F)(F)F)c2c3ccc(cc3[nH]c12)-c1ccc(nn1)N1CCS(=O)(=O)CC1

InChI Key InChIKey=UJGMROGDTTZZAX-JOCHJYFZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355419   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355419(CHEMBL1835152)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of JAK3 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355419(CHEMBL1835152)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in human HEL 92.1.7 irf1-bla cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355419(CHEMBL1835152)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of JAK2 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed