null
SMILES C[C@@H]1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2n1CCCN(C)C
InChI Key InChIKey=ZHMXXVNQAFCXKK-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50360301
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH
US Patent
Boehringer Ingelheim International GmbH
US Patent
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human RSK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of human PRKD2More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human LRRK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human PRKD1More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 714nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 161nMAssay Description:Inhibition of human RETMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 512nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 956nMAssay Description:Inhibition of human PDGFRaMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 219nMAssay Description:Inhibition of human PRKD3More data for this Ligand-Target Pair