null

SMILES O=C(Nc1ccncc1)c1ccc2cc3C(=O)NCCCn3c2c1

InChI Key InChIKey=FTOWCRNOCYACIS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361842   

TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM50361842(CHEMBL1938787 | US9150577, 156)copy SMILEScopy InChI
Affinity DataIC50: 39nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB22V6US Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50361842(CHEMBL1938787 | US9150577, 156)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of RSK2 phosphorylation by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4K7NPubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50361842(CHEMBL1938787 | US9150577, 156)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of RSK2-mediated CREB phosphorylation in HeLa cells expressing luciferase reporter geneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4K7NPubMed