null

SMILES COc1ccc(Nc2ncc3nc(Nc4ccccc4F)n(C4CCOCC4)c3n2)cc1

InChI Key InChIKey=QXNPNLLIZGVUPQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50363463   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363463(CHEMBL1946341)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363463(CHEMBL1946341)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363463(CHEMBL1946341)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of p38alpha using MBP and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363463(CHEMBL1946341)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed