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SMILES N[C@H]1CC[C@@H](CC1)Nc1ncc2nc(Nc3ccc(F)cc3F)n(C3CCCC3)c2n1

InChI Key InChIKey=MKUCYQPSROSPGD-SHTZXODSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50363467   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829SKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of p38alpha using myelin basic protein as substrate preincubated for 15 mins prior ATP addition measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829SKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of p38alpha using MBP and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZP6PubMed