null
SMILES C[C@H]([C@@H](C(=O)Nc1ccc(I)cc1F)n1c(O)c([nH]c1=O)-c1ccc(OC[C@H](O)CO)cc1)c1ccccc1
InChI Key InChIKey=BHCNYLYPOJYXCE-ZCPGDWHISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50365219
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Hoffmann-La Roche, Inc.
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of MEK1 in human LOX cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of MEK1 in human MIA PaCa-2 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of MEK1 in human H460 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Hoffmann-La Roche, Inc.
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of MEK1 in human HT-29 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair