null

SMILES C[C@H]([C@@H](C(=O)Nc1ccc(I)cc1F)n1c(O)c([nH]c1=O)-c1ccc(OC[C@H](O)CO)cc1)c1ccccc1

InChI Key InChIKey=BHCNYLYPOJYXCE-ZCPGDWHISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50365219   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of MEK1 in human LOX cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of MEK1 in human MIA PaCa-2 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of MEK1 in human H460 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MEK1 in human HT-29 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TNWPubMed