null
SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(cs2)-c2cccnc2OCc2ccc(OC(F)(F)F)cc2)cc1
InChI Key InChIKey=XSLQEOSGBAUMSK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50368990
Affinity DataIC50: 3.30E+4nMAssay Description:Inverse agonist activity at His6-tcs-human RORalpha LBD assessed as inhibition of biotinylated PGC1alpha (130 to 154 residues) peptide recruitment in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]ATRA from 6H-AVI-GST-TEV-human RORbeta (T221 to K470 residues) pre-incubated for 30 mins before [3H]ATRA addition and measurted a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Agonist activity at His6-tcs-human RORalpha LBD assessed as stimulation of biotinylated PGC1alpha (130 to 154 residues) peptide recruitment incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-2-(4-(ethylsulfonyl)phenyl)-N-(4-(2-(methoxymethyl)phenyl)thiophen-2-yl)acetamide from purified N-(HN)6-GST-TCS-human RORgammat ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inverse agonist activity at RORgammat in human TH17 cells assessed as inhibition of IL17 release incubated for 4 days by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inverse agonist activity at biotinylated HN-Avi-MBP-TCS-human RORgammat (258 to 518 residues) assessed as inhibition of biotinylated SRC-1 peptide NC...More data for this Ligand-Target Pair