null
SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(cs2)-c2cccnc2Oc2ccc(OC(F)(F)F)cc2)cc1
InChI Key InChIKey=KWCOHXDSOAWZFJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50369025
Affinity DataIC50: 3.30E+4nMAssay Description:Inverse agonist activity at His6-tcs-human RORalpha LBD assessed as inhibition of biotinylated PGC1alpha (130 to 154 residues) peptide recruitment in...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Agonist activity at His6-tcs-human RORalpha LBD assessed as stimulation of biotinylated PGC1alpha (130 to 154 residues) peptide recruitment incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Inverse agonist activity at RORgammat in human TH17 cells assessed as inhibition of IL17 release incubated for 4 days by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]-2-(4-(ethylsulfonyl)phenyl)-N-(4-(2-(methoxymethyl)phenyl)thiophen-2-yl)acetamide from purified N-(HN)6-GST-TCS-human RORgammat ...More data for this Ligand-Target Pair