null

SMILES COCc1ccc(cn1)-c1cc2c3n([C@H]4C[C@@H](C4)OC)c(=O)n(C)c3cnc2cc1F

InChI Key InChIKey=HAYQMMTYYBRDQT-WKILWMFISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50378194   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378194(CHEMBL4168290)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378194(CHEMBL4168290)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378194(CHEMBL4168290)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of ATR in human HT29 cells assessed as decrease in Chk1 phosphorylation at Ser 345 preincubated for 1 hr followed by 4NQO addition and mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed