null

SMILES Clc1ccc(s1)-c1ccc(Cn2ccnc2)cn1

InChI Key InChIKey=FDAVPEDTGURGBQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378945   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378945(CHEMBL2011263 | US9394290, 33)copy SMILEScopy InChI
Affinity DataIC50: 362nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H86US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378945(CHEMBL2011263 | US9394290, 33)copy SMILEScopy InChI
Affinity DataIC50: 362nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RJ2PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378945(CHEMBL2011263 | US9394290, 33)copy SMILEScopy InChI
Affinity DataIC50: 929nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RJ2PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378945(CHEMBL2011263 | US9394290, 33)copy SMILEScopy InChI
Affinity DataIC50: 929nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H86US Patent