null

SMILES O=Cc1ccc(s1)-c1ccc(Cn2ccnc2)cn1

InChI Key InChIKey=VILVKXGEHAYVOY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378946   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378946(CHEMBL2011264 | US9394290, 34)copy SMILEScopy InChI
Affinity DataIC50: 62nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H86US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378946(CHEMBL2011264 | US9394290, 34)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RJ2PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378946(CHEMBL2011264 | US9394290, 34)copy SMILEScopy InChI
Affinity DataIC50: 968nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RJ2PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378946(CHEMBL2011264 | US9394290, 34)copy SMILEScopy InChI
Affinity DataIC50: 968nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H86US Patent