null

SMILES COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)s1

InChI Key InChIKey=TZYSLHTWOJFPSJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50378979   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)copy SMILEScopy InChI
Affinity DataKd:  2.86E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 after 1 min by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0682GPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)copy SMILEScopy InChI
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0682GPubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD21DKPubMed
TargetC-C chemokine receptor type 4(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD21DKPubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378979(CHEMBL2011441)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD21DKPubMed