null

SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=VDTAJUONJQNBDK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380950   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA

LigandBDBM50380950(CHEMBL2016905)copy SMILEScopy InChI

Affinity DataIC50: 0.570nMMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

Curated by ChEMBL

LigandBDBM50380950(CHEMBL2016905)copy SMILEScopy InChI

Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN38W3PubMed