null

SMILES O[C@@H]1CCN(Cc2nc3c4cc(Br)ccc4oc3c(=O)[nH]2)C1

InChI Key InChIKey=FRRLLRQAGKSVMU-SECBINFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50383725   

TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of N-terminus Myc-tagged human CDC7 expressed in Escherichia coli by chemiluminescence assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4WS0PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of CDC7 in human MDA-MB-231T cells assessed as inhibition of MCM2 phosphorylation at Ser53 after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4WS0PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of N-terminal His-tagged human PIM2 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His-tagged human PIM3 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZHVPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383725(CHEMBL2030386)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminus His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4WS0PubMed