null
SMILES Nc1nc2ccc(cn2n1)-c1cncc(c1)S(=O)(=O)NCc1ccccc1
InChI Key InChIKey=JDIHUGWPWSWLOX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50389387
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kalpha by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of PI3Kdelta by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair