null

SMILES NC(=O)Nc1sc(cc1C(=O)N[C@H]1CCCNC1)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=LDNBXCSYCDEWSM-JTQLQIEISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389809   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389809(CHEMBL2070711)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389809(CHEMBL2070711)copy SMILEScopy InChI
Affinity DataEC50:  5.70E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389809(CHEMBL2070711)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed