null

SMILES CC(=O)c1ccc(cc1)-c1sc(NC(=O)NCCC(=O)NC(C)(C)C)nc1C

InChI Key InChIKey=IUPXLLWDLOWEBR-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50390410   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110gamma using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110beta using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataKi:  740nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110delta using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataKi:  1.89E+3nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of Vps34More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390410(CHEMBL2069328)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of PI4KbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61MRPubMed