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SMILES Clc1cccc(-c2c[nH]nn2)c1Cl

InChI Key InChIKey=OPIGATGRUCISOI-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50391364   

TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center for Cancer Research of the University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50391364(CHEMBL2148077)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KNWPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Ludwig Center for Cancer Research of the University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50391364(CHEMBL2148077)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KNWPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Ludwig Center for Cancer Research of the University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50391364(CHEMBL2148077)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KNWPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Ludwig Center for Cancer Research of the University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50391364(CHEMBL2148077)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human TDO transfected in mouse P815B clone 19 cells by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KNWPubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Ludwig Center for Cancer Research of the University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50391364(CHEMBL2148077)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KNWPubMed