null

SMILES [O-][N+](=O)c1ccc(CCN2CCN(CCc3ccc(cc3)[N+]([O-])=O)CC2)cc1

InChI Key InChIKey=GKZBQPSXHBJOPU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50391770   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 66nMT: 2°CAssay Description:FluxOR Kit Components (Invitrogen F10017) FluxOR Reagent (Component A) FluxOR Assay Buffer (Component B)-10x Concentrate PowerLo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VMHUS Patent
TargetInward rectifier potassium channel 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Kir2.1 expressed in HEK293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DZVPubMed
TargetInward rectifier potassium channel 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Kir2.3 expressed in CHO cells assessed as inhibition of 86Rb+ effluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DZVPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DZVPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2DF1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DZVPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [35S]MK-499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2DF1PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2DF1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [35S]MK-499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2DF1PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DZVPubMed