null

SMILES C[C@H](N)C1(O)CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=ROZUZKLWYFJFQI-VIFPVBQESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391800   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50391800(CHEMBL2146898)copy SMILEScopy InChI

Affinity DataIC50: 5.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed